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3-Dimensional Imaging At Nanometer Resolutions


Project Title3-Dimensional Imaging At Nanometer Resolutions
Track CodeU.S. Patent No. 7,675,045 (DOE S-112,966)
Short Description

Los Alamos National Laboratory - Express Licensing Program

An apparatus and method for enabling precise, 3-dimensional, photoactivation localization microscopy (PALM) using selective, two-photon activation of fluorophores in a single z-slice of a sample in cooperation with time-gated imaging for reducing the background radiation from other image planes to levels suitable for single-molecule detection and spatial location, are described.

Tags3-d, 3d, imaging, nanometer, resolutions
Posted DateApr 5, 2013 9:25 PM

Licensing Terms and Conditions

This patent is offered for Non-Exclusive licensing through Los Alamos National Laboratory's Express Licensing Program.  The financial terms for an Express License are listed below:

One-Time Non-Exclusive License Issue Fee:

Seven Thousand Five Hundred ($7,500) U.S. Dollars

Annual License Fee:

Five Hundred ($500) U.S. Dollars

Earned Royalties on Sales:

Two Percent (2.0%)

To submit a license request, please contact Laura Barber, Mike Erickson or Marcus Lucero at Upon receipt of an Express License request, LANL will review your request to ensure that it meets the Express Licensing requirements, and if so, will send you a copy of the non-negotiable Non-Exclusive License Agreement for execution.

Intellectual Property

Patent Number Issue Date Type Country of Filing
U.S. Patent No. 7,675,045 Mar 9, 2010 Utility United States