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Magnetospinning of micro and nano fibers

Details

Project TitleMagnetospinning of micro and nano fibers
Track Code2224
Short Description

The invention is a method & device combination for the fast spinning of fibers containing biological or biomedical loads, or specialty nano/microfibers. Due to the very high surface to volume ratio and the structure controlled at molecular level, nanofibers find applications in composite materials, catalysis, filtration and materials for biomedical use. Electrospinning methods are used to draw fine fibers by stretching small liquid droplets at high voltage. Electrospinning became the major nano-manufacturing method of ultrafine polymer fibers and composite fibers (including magnetic nanofibers) for cancer treatment, single cell manipulation, synthesis of magnetic nano-fibrous scaffolds for bone and tissue regeneration, tissue engineering, wound dressing, controlled drug release, design of magnetic grabbers, preparation of films with optical, electric and magnetic anisotropy, and composites for high performance water and air treatment  as well as several other medical and industrial applications.  However, electrospinning suffers many drawbacks. For instance, it requires the use of solvents with high-dielectric constants which limits the nature of solvents (and, thus, of the polymers) that can be used; its application to conductive polymers and polymer composites is also limited due the degradation of electrostatic forces; and the use of high potentials often leads to degradation of biologic materials—such as cells—that are embedded in the fibrous matrix.

Abstract

In order to circumvent the drawbacks associated with electrospinning, UGA researchers developed a new, voltage-independent method for the high-speed spinning of nano– and micro-fibers. The method, magneto-spinning, is based on the formulation of polymer-based ferrofluids containing—for instance— biocompatible ferromagnetic materials. These ferrofluids can be spun at high speeds to form long fibers (> 50 m/minute/nozzle, in lab scale) which can be impregnated with a plurality of loads such as stem cells, proteins, nanotubes, fluorescent and phosphorescent materials, graphite, graphene, and therapeutic agents, to name a few. Virtually any polymer/solvent combination can be used, as the method is independent of the dielectric constant of the material to be spun. For instance, nanofibers of poly(ethylene oxide) - PEO, poly(methyl methacrylate) - PMMA, polycaprolactones, carrying myriad of different loads were manufactured by this method. This scalable method is embodied by a simple and inexpensive device. The method has been adapted for the spinning of fibers without a ferromagnetic fluid, thus greatly enhancing the applicability of the method.

 

               

References and Intellectual Property:

 
Tagstextiles, nanotechnology, fiber, spinning, device, gauze, Bandage, medical, stem cells
 
Posted DateNov 14, 2017 3:31 PM

People

Name
Gennaro Gama